Castillo originally auditioned for the role of Delores Padilla when GH's casting director, Mark Teschner noticed her on Franklin & Bash.She actually did a chemistry test with her current co-star, Jason Thompson, who portrayed Patrick.She also had a son named, Gabriel Santiago, who died shortly after his birth in 2014, with her ex-fiancé, Dr. Patrick's sister-in-law Maxie Jones, however, can't babysit his daughter Emma, so Britt suggests that Sabrina can babysit.When Sabrina goes to babysit, Emma is shy and not happy about her dad going on a date, so soon after her mom, Robin, has seemingly died.And they are either going to love it or kick me out for not taking this seriously.” So I just did it with a lisp. And the scene was with Jason, and I could see it in his eyes that he wanted to burst into laughter.At the end when they cut, I just heard Frank’s voice over the loud speaker going, “That was awesome, Teresa.” I was so pleased with what I had done." -Castillo on her creative audition.
She was portrayed by actress Teresa Castillo from the character's debut on September 19, 2012 until September 23, 2016.
Apart from her feelings for Patrick, Sabrina's whole life is defined by following in her mother's footsteps and becoming a nurse.